California, Oregon and Washington announced plans on Wednesday to form a “health alliance” that would coordinate vaccine recommendations for the three states at a time of unparalleled turmoil at the Centers for Disease Control and Prevention, the federal agency responsible for issuing vaccine guidance for the country.

The alliance is intended to provide residents with scientific data about vaccine safety and efficacy, and to issue guidance on vaccines for respiratory illnesses like Covid and the flu, as well as an array of childhood immunizations.

In a joint statement, governors of the three states said that the C.D.C. had become “a political tool that increasingly peddles ideology instead of science, ideology that will lead to severe health consequences.” The agency has lost thousands of employees since January, most recently its director.

The governors said the new alliance would protect against what they called the “politicization of science” by helping families, medical providers and vaccine manufacturers plan for the future using “consistent, science-based recommendations they can rely on — regardless of shifting federal actions.”