Research into the glymphatic (The rather recently discovered brain lymphatic system) is one of the more fascinating frontiers of research going on right now, we’ll be finding for decades to come the effects it has on mental health and brain diseases.

Jacobs ladder had quite a few more scenes in it that were cut because test audiences found them too disturbing, theres a whole extra sequence between the meeting with the chemist and him returning home that you can find in the deleted scenes on youtube. Honestly I always thought that the demons and horror elements were creative, but ultimately a bit tame. The intro is really strong with the subway bit and all the anti-drug posters, and then the car scene is fantastic but after that the whole thing kind of loses steam with the kid and ex-wife dream sequence. It was too grounded to be a surrealist film but also too surreal to be a grounded film, it could have done with being trimmed of the ending and dead kid story and focused more on the other story lines.

Also Tim Robbins has the most unconvincing fake laugh in the movie I’ve ever heard.

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Enterprise is so unintentionally hilarious because of things like the sex airlock, especially the fact that Dr Phlox is banned from it for not being hot enough, so he gets a little window to do his scenes for it. The funniest moment in the entire show is the bit where Hoshi’s shirt gets fully ripped off while crawling around in vents for zero reason, or the reveal in the mirror universe episodes with the womens uniforms just having no torso? It really does it to such a severe degree that it makes a rather forgettable show about Star Trek dealing with 9/11 endlessly rewatchable in “So bad its good” way.

Sidenote I always thought the funniest thing in DS9 was Jake motherfucking Sisko running around in the background being a smooth-talking Dom-Jot hustler poet who immediately goes from getting a Dabo Girl girlfriend at like 16 to hitting on Kira the next episode because of Mrs Rodenberry’s psychic pheromones.

The bait worked, its like chum in the water

I’m going as King Harold Godwinson. Am I a moron? Does ANYONE know who that is?

Any UK/France/Ireland school goers will have had 1066 drilled into their skulls for about a year.

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Successful runs of Maxed Workers and Resources should get you a city planning degree automatically

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FIRE OF WROTH

He calls you Detective when he’s happy

They’ve started live testing server meshing and its hilarious because when it actually works you realise they didnt design any facet of the game for more than 20 players at a time. There literally arnt enough habs for people to spawn in, way to little elevators and screens. Everything is diagetic but in such limited quantities that when they did the 1000 player test (Which only got to 750 before crashing) people had to form actual queues to use the terminals to spawn ships. Unlike a lot of people I’m pretty confident they’ll eventually release a proper game I just dont think it will be any fun at all. They just keep making the game more and more tedious in the name of “realism”.

If they can reverse engineer IRN BRU then I believe they can do anything

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Yeah but its not like October 7th would happen in 2024 NI, Loyalist support of Israel is simply a reactionary stance brought on by Nationalist support of Palestine. I think the reason is more that he is, like many people here, incredibly adverse to paramilitary violence. It’s easy to see how a person with a Loyalist background with a “civility” mindset could be shocked into returning to their traditional Right Wing Loyalist roots when seeing the Left wing Nationalists support what they see to be a unforgivable act of violence similar to the Troubles.

Then again who the fuck knows maybe he got converted by Facebook or is just being opportunistic, maybe he recently got married or divorced or a million other personal things that lead to these kinds of changes.

Except the Anglos will be the last to suffer from this, when it comes to this sort of thing the order of getting shat on goes Northern Ireland, Wales, Scotland and then England. In NI right now the NHS has already collapsed effectively, even vital stuff like cancer treatments are now at the point where people are dying on the wait lists, all its going to take is the introduction of privatised A&E and it’ll all be gone.

#Tradle #830 1/6 🟩🟩🟩🟩🟩 https://oec.world/en/games/tradle

Me and my friend are from here and even he didn’t realise where it was, so I can see how it might trip people up

For the purposes of HRT, regardless of application, there are two main estrogens to consider; Estrone (E1) and Estradiol (E2).

Estrone is a weak estrogen in the body it is derived from cholesterol. However, in its most common form of medication, Premarin, it is derived from the urine of pregnant mares. As a weak estrogen that is also not bioidentical (Premarin’s chemical structure differs from organic estrone) , it is not as effective as Estradiol in the role of HRT.

Estradiol is the major female sex hormone and as such in it’s synthesised ester forms such as Estradiol Valerate it is often considered the most effective form of HRT. It can be derived from diosgenin found in yams, or stigmaserol usually from soybean oil and probably some other plant precursors Im not aware of. It should be noted that most sex hormones can be derived from these methods, stigmaserol for example converts to estrone before it is chemically altered to estradiol.

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I’ve been on a binge of 90s games this year and its really impressive how well they still hold up, Half Life 1, Deus Ex, Morrow wind (I think it says alot that Morrowind still has a thriving mod community and a completely rewritten open source version), Just last week I found out they made talkie mods for the first two Monkey Islands, so I’m playing through those too. It’s crazy that my 2023 GOTY was the System Shock remake. Point and clicks really are the pinnacle of game design tbh, all the games that have stuck with me over the last through years from Norco to Disco Elysium are essentially just point and clicks.