My brother is opioid resistant and has constant back pain. What he really needs is fentanyl but can’t get it due to widespread abuse. Same reason you can’t get Ambien after Tiger Woods took it and drove his Rolls-Royce into a ditch. The cops found him sound asleep with the engine running.
Resistance is a real thing, but that’s not lacking the receptor. It can be caused by loads of shit from small mutations reducing binding affinity, metabolic differences decreasing halflife, or weird brain shit that reduces the analgesia because you just process pain differently.
Firstly cheers for like slopjacketting me, idk why you think that I’m just writing what I know dickhead.
Secondly you said you don’t have the receptor, and continuing on from that you said your brother has resistance. I was trying to be polite to you by giving you an out from being stupendously wrong by opening the “Oh you might be confused by what resistance entails and how it’s different from lacking the receptor” door.
My brother is opioid resistant and has constant back pain. What he really needs is fentanyl but can’t get it due to widespread abuse. Same reason you can’t get Ambien after Tiger Woods took it and drove his Rolls-Royce into a ditch. The cops found him sound asleep with the engine running.
Resistance is a real thing, but that’s not lacking the receptor. It can be caused by loads of shit from small mutations reducing binding affinity, metabolic differences decreasing halflife, or weird brain shit that reduces the analgesia because you just process pain differently.
If I wanted AI slop I’d ask myself, you don’t have to copy-paste. Humans only.
Firstly cheers for like slopjacketting me, idk why you think that I’m just writing what I know dickhead.
Secondly you said you don’t have the receptor, and continuing on from that you said your brother has resistance. I was trying to be polite to you by giving you an out from being stupendously wrong by opening the “Oh you might be confused by what resistance entails and how it’s different from lacking the receptor” door.
No good dead goes unpunished I guess.