No. Some positions have cabinet-level ranks (not press secretary) like chief of staff, but being on the cabinet itself requires being the head of one of the major administrative departments. Pretty much any of them can do significant damage with the wrong person installed.
Yeah, very handy for bots. People, however, tend to have online identities or personas that they will try to carry forward on account names they create.
Burner accounts notwithstanding, of course.