Ublock Origin is an obvious one, but I also can’t stand not having Foxy Gestures anymore. It adds customizable mouse gestures, so you can set it up to have easy swipes to go back a page, reload a page, close a tab, etc, and it feels wonderful and smooth to use compared to just using the traditional buttons to do everything. Honestly it’s kinda wild to me that this isn’t more popular now that people are so used to phone gestures. It’s good for the same reasons!
I don’t know what filters you have specifically enabled, but I have all EasyList Annoyances and uBlock Annoyance lists enabled and they work fine. There may sometimes be something that these don’t get, but that happens quite rarely.