Erythritol may impair cellular functions essential to maintaining brain blood vessel health, according to researchers at the University of Colorado Boulder. Findings suggest that erythritol increases oxidative stress, disrupts nitric oxide signaling, raises vasoconstrictive peptide production, and diminishes clot-dissolving capacity in human brain microvascular endothelial cells.
Pretty sure another study found Xylitol might have the same issue. I’m personally avoiding sugar alcohols at this point. That said, it severely limits sweetener options for people that have blood sugar issues.