The regulation calls out 19 vehicle functions which must have physical controls inside the vehicle, with additional requirements about size and usability of the buttons.
Those functions include:
Turn signals
Hazard lights
Horn
PRND gear shifter
Driver assist function, if present
Windshield wipers
Windshield defroster
Power windows
Emergency call system
Power off switch for EVs
That might be more of a culture things, i grew up with manuals and pulling the handbrake and putting it into first or reverse is still second nature to me and I’d think most people here. If anything the introduction of the auto handbrake is causing people to lose the habit.
But with my car I don’t really see how anyone could make a mistake. If you open the door in anything other than park, it screams at you. If you are in park and open it then it loudly applies them.