In Buddhist teachings, desire leads to suffering. For example, the desire for wealth may lead one to do dangerous things, hurting themself, or to exploit others, causing them suffering. So the aim of Buddhism is to transcend desire by following the ‘Eightfold Path’ (right thought, right action, etc.). When desire has been controlled, one will ‘want’ nothing, and can escape ‘samsara’ (wordly pressures; often compared to a wheel since it involves cycles of action and reaction, cause and effect) to reach ‘nirvana’ (a state of calm, bliss, peace, etc.). The meme is pointing out that one who truly wants nothing will also not want social media recognition for it.

In Buddhism the “goal” is to not want. To have no desire. Desiring things is the root of all suffering and what keeps you tethered to “samsara” the cycle of birth, life, death and rebirth. (It’s a cycle so its a “wheel”.)

By following the eight fold path (Buddhist religious tenets) you give up desire and reach nirvana. A state of total detachment and the end of desire and therefore of suffering.
The joke here is that one person asserts that mommy desires nothing (Either as self identification, or as a joke about being unable to please someone in a dom/sub situation), and the response in the community note is that if she needs to tell people she has no desires she manifestly still has a desire for recognition.

It isnt funny imo, but none of my jokes are either so 🤷

There is a running gag on Twitter/Bluesky that Sabre is secretly post-transition Kurt Cobain, so we’re balls deep into simulacrum territory with the Nirvana jokes