Thank you Mr Kojima, amazing writing

  • queermunist she/her@lemmy.ml
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    1 day ago

    If you’re already on an antiandrogen, what good is a DHT blocker like dutasteride? DHT is synthesized from T, if you don’t have T you don’t have DHT.

    I am not an endoctrinologist so idk maybe I’m super wrong. 🤷‍♀️

    • EmmaGoldman [she/her, comrade/them]@hexbear.net
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      19 hours ago

      Your antiandrogen doesn’t block 100% of T and isn’t supposed to. The goal of the antiandrogen part of feminizing HRT is to reduce T levels to the typical female range. The female range is like 10-70 ng/dL where the male range is like 250-900 ng/dL.

      In fact, many common antiandrogens like spironolactone or bicalutimide don’t block production at all, they block the androgen receptors. GnRH antagonists actually block the production of sex hormones, but they’re less commonly used for HRT.

      Since your body will still have some testosterone, a DHT blocker will prevent it from being synthesized into DHT and thus can help restore miniaturized hair follicles.