It’s been a long while since i used a desktop and honestly can’t remember what antivirus software i used, and even then, probably the landscape has changed over the years.
Atm i’ve been winging it with just Windows Defender (no custom configuration) and scanning any thing that looks suspicious on VirusTotal, but probably that would be not enough.
I’m thinking on get a couple of pirated files, so i’d like to be as secure as possible.
Aside from other recommendations, not installing the latest stuff and waiting a couple of days or longer can help, since open source projects have sometimes been infected too. Especially if it’s pirated files.