Lemmy.one
  • Communities
  • Create Post
  • heart
    Support Lemmy
  • search
    Search
  • Login
  • Sign Up
fossilesque@mander.xyz to Science@mander.xyzEnglish · il y a 1 an

Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

news.emory.edu

external-link
message-square
32
fedilink
  • cross-posted to:
  • hackernews@lemmy.bestiver.se
151
external-link

Psilocybin delays aging, extends lifespan, new Emory study suggests | Emory University | Atlanta GA

news.emory.edu

fossilesque@mander.xyz to Science@mander.xyzEnglish · il y a 1 an
message-square
32
fedilink
  • cross-posted to:
  • hackernews@lemmy.bestiver.se
Emory University researchers identified that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms, actively delays aging in cells and organisms.
alert-triangle
You must log in or # to comment.
  • Riddick3001@lemmy.world
    link
    fedilink
    arrow-up
    40
    ·
    il y a 1 an

    We should live in Shroom world, everybody will be connected by the mycelium, live long and prosper together.

    • NaibofTabr@infosec.pub
      link
      fedilink
      English
      arrow-up
      20
      ·
      il y a 1 an

      Yes… let the cordyceps eat your brain… become one with the omnifungi… let our will become yours… listen to the mold as it whispers in your mind…

      • Mac@mander.xyz
        link
        fedilink
        English
        arrow-up
        9
        ·
        il y a 1 an

        🤷‍♂️

        Okay, sure, why not

      • Vanilla_PuddinFudge@infosec.pub
        link
        fedilink
        English
        arrow-up
        3
        ·
        il y a 1 an

        Eh, beats fascism.

      • steal_your_face@lemmy.ml
        link
        fedilink
        English
        arrow-up
        2
        ·
        il y a 1 an

        I am the Globglogabgalab

      • lb_o@lemmy.world
        link
        fedilink
        arrow-up
        2
        ·
        il y a 1 an

        WE ARE THE ONE!

      • otter@lemmy.dbzer0.com
        link
        fedilink
        English
        arrow-up
        1
        ·
        il y a 1 an

        Did you drop this? /s

        You’re making it sound pretty damn amazing, frankly. Have you looked around lately? 😅😶‍🌫️

      • Mac@mander.xyz
        link
        fedilink
        English
        arrow-up
        0
        ·
        edit-2
        il y a 1 an

        edit: double post

  • jeffw@lemmy.world
    link
    fedilink
    arrow-up
    28
    ·
    il y a 1 an

    Forgive me for doubting any studies that don’t involve blinded trials… but this is just one study. Let’s see if it can be replicated before we get excited

    • remotelove@lemmy.ca
      link
      fedilink
      arrow-up
      13
      ·
      il y a 1 an

      Oh, I am going to try to replicate this study. I’ll hit you back in about 50 years if it worked.

      • jeffw@lemmy.world
        link
        fedilink
        arrow-up
        2
        ·
        il y a 1 an

        It takes you 50 years to transform into a mouse?

        • remotelove@lemmy.ca
          link
          fedilink
          arrow-up
          1
          ·
          il y a 1 an

          Or sooner, once the medicine kicks in.

          • jeffw@lemmy.world
            link
            fedilink
            arrow-up
            1
            ·
            il y a 1 an

            Whoa. You’re a mouse now?

  • Laser@feddit.org
    link
    fedilink
    arrow-up
    9
    ·
    il y a 1 an

    A newly published study in Nature Partner Journals’ Aging demonstrates that psilocin, a byproduct of consuming psilocybin, the active ingredient in psychedelic mushrooms,

    Maybe my memory is wrong, but I had it the other way around: Psilocin is the active substance, but its not very stable. Psilocybin gets metabolized to Psilocin. Calling it a “byproduct” is kind of underselling it. Psilocybin itself isn’t active by itself.

    Quick wiki check confirms this. I always have troubles with articles opening with. I can’t even read that as unfortunate wording.

  • BodyBySisyphus [he/him]@hexbear.net
    link
    fedilink
    English
    arrow-up
    8
    ·
    il y a 1 an

    Results indicated that the mice that received an initial low dose of psilocybin of 5 mg/kg, followed by a monthly high dose of 15 mg/kg for 10 months, had a 30% increase in survival compared to mice who hadn’t received any.

    So if we take a standard 80 kg adult male, 80 * 15 mg = 1.2 g, which sources indicate is enough for a standard trip. That’s also like almost half an ounce of dried mushrooms. Time to start tripping… for science.

    • HootinNHollerin@lemmy.dbzer0.com
      link
      fedilink
      English
      arrow-up
      5
      ·
      il y a 1 an

      1 oz is 28.35 g

      • BodyBySisyphus [he/him]@hexbear.net
        link
        fedilink
        English
        arrow-up
        8
        ·
        il y a 1 an

        Yeah, the paper is talking about pure Psilocybin. I double checked and the rule of thumb is around 1% psilocybin by dry weight so I was actually off and you’d need closer to three ounces.

        • Castor_Troy [comrade/them,he/him]@hexbear.net
          link
          fedilink
          English
          arrow-up
          4
          ·
          edit-2
          il y a 1 an

          (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

          1200 mg psilocybin * (1 g psilocybin / 100 g dried mushrooms) = 12 g dried mushrooms

          I think it’s 12 grams dried mushrooms, which is almost half an ounce, like you first said.

          • Maturin [any]@hexbear.net
            link
            fedilink
            arrow-up
            7
            ·
            il y a 1 an

            Shouldn’t it be 1200 mg / 0.01 = 120 g of dried mushrooms?

            • Castor_Troy [comrade/them,he/him]@hexbear.net
              link
              fedilink
              English
              arrow-up
              2
              ·
              il y a 1 an

              Thank you. I was staring at it and knew the units weren’t canceling out. That’s an insane dose though.

              • Maturin [any]@hexbear.net
                link
                fedilink
                arrow-up
                4
                ·
                il y a 1 an

                Even the “low dose” is the equivalent of almost 2 oz per dose. Those mice got to convene with the mice gods on the reg I’m sure.

                • propter_hog [any, any]@hexbear.net
                  link
                  fedilink
                  English
                  arrow-up
                  4
                  ·
                  il y a 1 an

                  Boofing a whole tray of penis envy shrooms… for science

            • Castor_Troy [comrade/them,he/him]@hexbear.net
              link
              fedilink
              English
              arrow-up
              2
              ·
              il y a 1 an

              (15 mg psilocybin / 1 kg body weight) * 80 kg body weight = 1200 mg psilocybin

              1200 mg psilocybin = 1.2 g psilocybin * (100 g dried mushrooms / 1 g psilocybin) = 120 g dried mushrooms

              There we go.

  • Torn Apart By Dogs@lemmy.blahaj.zone
    link
    fedilink
    English
    arrow-up
    8
    ·
    il y a 1 an

    HOLY SHIT IM GONNA LIVE FOREVER

  • wideopenarms [he/him]@hexbear.net
    link
    fedilink
    English
    arrow-up
    5
    ·
    edit-2
    il y a 1 an

    Idc, I’ll just die old, no one’s ever gonna get me to willingly take hallucinogens

    Go ahead and hit me with the downbear, don’t care if that’s an L take or not

    • otter@lemmy.dbzer0.com
      link
      fedilink
      English
      arrow-up
      2
      ·
      il y a 1 an

      You do you. Have fun!

    • isolatedscotch@discuss.tchncs.de
      link
      fedilink
      arrow-up
      2
      ·
      il y a 1 an

      no healthy adult should feel the need to take any drug

      • Rivalarrival@lemmy.today
        link
        fedilink
        English
        arrow-up
        1
        ·
        il y a 1 an

        Need? Of course not. Desire? Certainly.

  • Ogmios@sh.itjust.works
    link
    fedilink
    arrow-up
    5
    ·
    edit-2
    il y a 1 an

    deleted by creator

    • BurgerBaron@piefed.social
      link
      fedilink
      English
      arrow-up
      16
      ·
      il y a 1 an

      You’d have to microdose regularly for it to matter if it actually does anything in humans for our telomeres.

      • Ogmios@sh.itjust.works
        link
        fedilink
        arrow-up
        3
        ·
        edit-2
        il y a 1 an

        deleted by creator

        • BurgerBaron@piefed.social
          link
          fedilink
          English
          arrow-up
          6
          ·
          il y a 1 an

          Your sarcasm is noted, but seems daft when you suggest you’ll live longer because you ate a funny mushroom a couple times.

          • Ogmios@sh.itjust.works
            link
            fedilink
            arrow-up
            1
            ·
            edit-2
            il y a 1 an

            deleted by creator

  • Bronzebeard@lemmy.zip
    link
    fedilink
    arrow-up
    3
    ·
    il y a 1 an

    Nuh uh. I’ve seen the Last of US. We all know where this ends up

  • Hirom@beehaw.org
    link
    fedilink
    arrow-up
    1
    ·
    il y a 1 an

    Wake me up when once there are results of a well-designed clinical trial.

    My understanding of the article is they’re extrapolating from experiments on mice and on a few human cells in a lab.

Science@mander.xyz

science@mander.xyz

Subscribe from Remote Instance

Create a post
You are not logged in. However you can subscribe from another Fediverse account, for example Lemmy or Mastodon. To do this, paste the following into the search field of your instance: !science@mander.xyz

General discussions about “science” itself

Be sure to also check out these other Fediverse science communities:

https://lemmy.ml/c/science

https://beehaw.org/c/science

Visibility: Public
globe

This community can be federated to other instances and be posted/commented in by their users.

  • 39 users / day
  • 498 users / week
  • 1.42K users / month
  • 3.78K users / 6 months
  • 52 local subscribers
  • 7.27K subscribers
  • 2.15K Posts
  • 7.51K Comments
  • Modlog
  • mods:
  • Salamander@mander.xyz
  • BE: 0.19.7
  • Modlog
  • Legal
  • Instances
  • Docs
  • Code
  • join-lemmy.org